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Postdoctoral Scientist - Metastatic Niche, KS Chan lab

Company: CEDARS-SINAI
Location: Huntington Beach
Posted on: November 16, 2022

Job Description:

Grow your career at Cedars-Sinai!Cedars-Sinai is a nonprofit academic healthcare organization serving the diverse Los Angeles community and beyond. We are one of the leading institutes for competitive research funding from the National Institutes of Health. As an international leader in biomedical research, we translate discoveries into successful treatments with global impact. Cedars-Sinai is a hub for biomedical research with discoveries occurring in 26 departments and institutes that encompass the full spectrum of medicine.Dr. Keith Syson Chan's laboratory is seeking multiple postdoctoral scientists to join their dynamic team in sunny California! Syson Chan lab is comprised of an interdisciplinary team () focusing on cancer research that can be translated into early-phase clinical trials or biomarkers to impact patients. We integrate innovative single-cell technologies and various study models (e.g., patient-derived xenografts, syngeneic murine models, GEMM) to address key research questions spanningTo characterize a newly discovered metastatic niche [Nature Communications 10: 2131 (2019) and Nature Reviews Urology 2022 ] its interaction with other myeloid cells in the microenvironment to modulate metastatic lung colonization. This project builds on existing RNA seq profiling of tumor and niche cells from human patients and mouse models, with established in vivo metastatic patient-derived xenograft and syngeneic models, accessibility to state-of-the-art multiplex imaging and microfluidic systems to recreate 3D microenvironment in vitro, and other organoid models for investigating mechanism-based therapies. An ideal applicant will be have expertise in the metastatic cascade or tumor microenvironment, familiar with techniques e.g., FACS, 2D/3D culturing systems, interests in the collagen scaffold/mechanobiology or molecular biology is highly preferred.https://jobs.cedars-sinai.edu/job/los-angeles/postdoctoral-scientist-metastatic-niche-cancer-institute/252/11344550496To learn more:

  • Cedars-Sinai Cancer ranks #2 in the nation

  • Primary Duties and Responsibilities:
    • The design of research directions and experiments in cooperation with the mentor. Will keep appropriate experimental records and analyze the results with the PI.
    • Explore literatures and state-of-the-art techniques relevant to the project.
    • Compiling figures and text for the submission of publications and presentations as primary author or co-author.
    • Highly encouraged to apply for fellowship or career transition grant application for career advancement.Essential Job Responsibilities:
      • Participate and present at lab meetings, research-oriented interest groups, and attend departmental or cancer center seminar seriesEducation:
        • Doctorate (MD, PhD, VMD, or DDS) in biomedical sciences, cancer biology or immunology.#job
          Working Title:Postdoctoral Scientist - Metastatic Niche, KS Chan lab
          Department:Home Dept - Hem - Onc
          Business Entity:Academic / Research
          Job Category:,Academic/Research,Academic/Research
          Job Specialty:Postdoctoral
          Position Type:Full-time
          Shift Length:8 hour shift
          Shift Type:Day

Keywords: CEDARS-SINAI, Huntington Beach , Postdoctoral Scientist - Metastatic Niche, KS Chan lab, Healthcare , Huntington Beach, California

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